First Time User? Sign Up Now
First Time User? Enroll now.
Home > Health Library > Nitrates for Coronary Artery Disease
Nitrates open (dilate) the arteries to
the heart. This increases blood flow to the heart, relieving angina symptoms such as chest pain or pressure.
Nitrates also dilate veins throughout the body so that
they can hold more blood. This reduces the amount of blood going back to the
heart, reducing the heart's workload.
Nitrates are used to:
Nitrates can relieve angina symptoms and may improve quality of life.footnote 1
If the usual dose of nitroglycerin does not relieve your symptoms, it might mean that the angina may be getting worse or becoming
unstable. If this happens, call your doctor
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call 911 or other emergency services right away if you have:
Call your doctor right away if you have:
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug
Reference is not available in all systems.)
Nitroglycerin can help you manage symptoms of angina. Nitroglycerin for angina is taken as a
pill or a liquid spray. Skin patches or paste are also available to prevent
angina. For more information, see:
Do not take an erection-enhancing medicine such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra) if you are taking a nitrate. Combining these two drugs can cause a life-threatening drop in blood pressure.
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
If you are pregnant, breastfeeding, or planning to get pregnant, do not use any medicines unless your doctor tells you to. Some medicines can harm your baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all your doctors know that you are pregnant, breastfeeding, or planning to get pregnant.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
Complete the new medication information form (PDF)( What is a PDF document? ) to help you understand this medication.
O'Toole L (2008). Angina (chronic stable), search date June 2007. Online version of BMJ Clinical Evidence: http://www.clinicalevidence.com.
Current as ofJuly 22, 2018
Author: Healthwise StaffMedical Review: Rakesh K. Pai, MD, FACC - Cardiology, ElectrophysiologyMartin J. Gabica, MD - Family MedicineE. Gregory Thompson, MD - Internal Medicine
Current as of:
July 22, 2018
Medical Review:Rakesh K. Pai, MD, FACC - Cardiology, Electrophysiology & Martin J. Gabica, MD - Family Medicine & E. Gregory Thompson, MD - Internal Medicine
To learn more about Healthwise, visit Healthwise.org.
© 1995-2018 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
UNC Medical Center
101 Manning Drive
Chapel Hill, NC 27514
UNC Health Care Citrix
UNC Medical Center Intranet
Copyright 2019 UNC Health Care. All rights reserved.