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pentosan polysulfate sodium

Pronunciation: PEN toe san POL ee SUL fate SOE dee um

Brand: Elmiron

Elmiron

slide 1 of 2, Elmiron,

100 mg, capsule, white, imprinted with BNP 7600

Image of Elmiron
slide 1 of 2
    

Elmiron

slide 2 of 2, Elmiron,

100 mg, white, imprinted with BNP 7600

Image of Elmiron
slide 2 of 2
    

What is the most important information I should know about pentosan polysulfate sodium?

Taking this medicine can make it easier for you to bleed. Call your doctor at once if you have any unusual bleeding (nosebleed, blood in your urine or stools, rectal bleeding, coughing up blood, bleeding gums).

What is pentosan polysulfate sodium?

Pentosan polysulfate sodium works like an anticoagulant (blood thinner) that prevents the formation of blood clots. However, it is used to treat bladder pain and discomfort caused by cystitis (bladder inflammation or irritation).

Pentosan polysulfate sodium is for use in adults and children at least 16 years old.

Pentosan polysulfate sodium may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking pentosan polysulfate sodium?

You should not use pentosan polysulfate sodium if you are allergic to it.

Tell your doctor if you have ever had:

  • a bleeding or blood clotting disorder;
  • an aneurysm or stroke;
  • a stomach ulcer, intestinal polyps or diverticulitis; or
  • liver disease.

Tell your doctor if you are pregnant or breastfeeding.

How should I take pentosan polysulfate sodium?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take the medicine on an empty stomach, at least 1 hour before or 2 hours after a meal.

Take this medicine with a full glass of water.

Swallow the delayed-release capsule whole and do not crush, chew, break, or open it.

Your doctor will need to check your progress every 3 months to help determine how long to treat you with pentosan polysulfate sodium. You may also need blood tests to check for certain side effects.

If you need surgery, tell your surgeon you currently use this medicine. You may need to stop for a short time.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking pentosan polysulfate sodium?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of pentosan polysulfate sodium?

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • nosebleeds;
  • blood in your urine or stools;
  • rectal bleeding;
  • coughing up blood;
  • bleeding gums; or
  • a light-headed feeling, like you might pass out.

Common side effects may include:

  • bruising, blood in your stools;
  • hair loss;
  • nausea, diarrhea, upset stomach;
  • headache;
  • swelling, weight gain;
  • dizziness;
  • rash; or
  • abnormal liver function tests.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect pentosan polysulfate sodium?

Tell your doctor about all your other medicines, especially:

  • a blood thinner --warfarin, Coumadin, Jantoven;
  • medication used to prevent blood clots --apixaban, rivaroxaban, Eliquis, Xarelto, and others; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect pentosan polysulfate sodium, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about pentosan polysulfate sodium.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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