First Time User? Sign Up Now
First Time User? Enroll now.
Home > Health Library > Typhoid Vaccines: What You Need to Know
Typhoid (typhoid fever) is a serious disease. It is caused by bacteria called Salmonella Typhi.
Typhoid causes a high fever, fatigue, weakness, stomach pains, headache, loss of appetite, and sometimes a rash. If it is not treated, it can kill up to 30% of people who get it.
Some people who get typhoid become "carriers" who can spread the disease to others.
Generally, people get typhoid from contaminated food or water. Typhoid is rare in the U.S., and most U.S. citizens who get the disease get it while traveling. Typhoid strikes about 21 million people a year around the world and kills about 200,000.
Typhoid vaccine can prevent typhoid.
There are two vaccines to prevent typhoid. One is an inactivated (killed) vaccine gotten as a shot.
The other is a live, attenuated (weakened) vaccine which is taken orally (by mouth).
Routine typhoid vaccination is not recommended in the United States, but typhoid vaccine is recommended for:
Inactivated typhoid vaccine (shot)
Live typhoid vaccine (oral)
Either vaccine may safely be given at the same time as other vaccines.
Ask your doctor for more information.
Like any medicine, a vaccine could cause a serious problem, such as a severe allergic reaction. The risk of typhoid vaccine causing serious harm, or death, is extremely small. Serious problems from either typhoid vaccine are very rare.
Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. These would start a few minutes to a few hours after the vaccination.
VAERS is only for reporting reactions. They do not give medical advice.
Vaccine Information Statement
Department of Health and Human Services
Centers for Disease Control and Prevention
Many Vaccine Information Statements are available in Spanish and other languages. See www.immunize.org/vis.
Hojas de información sobre vacunas están disponibles en español y en otros idiomas. Visite www.immunize.org/vis.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
UNC Medical Center
101 Manning Drive
Chapel Hill, NC 27514
UNC Health Care Citrix
UNC Medical Center Intranet
Copyright 2020 UNC Health Care. All rights reserved.