Varicella-Zoster Immune Status

Gold Top

Tube Type

Test ID   LAB162
EPIC Order
  Varicella Zoster Antibody IgG
CPT Code(s)   86787
Group/Individual Test   Individual
Laboratory   Clinical Immunology
Tube Station   30
Specimen Routine: 3 mL blood/serum separator tube/gold top; see important Comments
Availability Routine: Monday-Friday
Turnaround Time   1-4 Days (Routine)
Reference Range    

Specimens submitted for VZV Immune Status testing are assayed using a qualitative, chemiluminescence immunoassay for the detection of IgG antibodies to VZV virus in human serum.  The test is intended as an aid in the determination of previous infection with VZV.  Performance in individuals vaccinated with VZV is not defined.  Results are reported as negative, positive or equivocal.   A negative result indicates no detectable VZV antibody, but does not rule out acute infection. It should be noted that the test usually scores negative in infected patients during the incubation period and the early stages of infection.   If exposure to varicella-zoster virus is suspected, despite a negative finding, a second sample should be collected and tested no less than one or two weeks later.  Positive results indicate the presence of detectable VZV IgG antibodies. A positive result generally indicates exposure to the pathogen or administration of specific immunoglobulins, but it is no indication of active infection or stage of disease.  Equivocal results should prompt collection of a new sample for repeat testing.

Reviewed by jcarr on November 30, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514