Toxoplasma IgG

• Specimens for Toxoplasma gondii IgG antibody testing are assayed with a qualitative assay, chemiluminescent immunoassay for the detection of IgG antibodies.   
• IgG antibodies generally appear 1-2 weeks after the infection, reach a peak in 6-10 weeks and persist at various levels for the rest of the life of the host. This test is intended as an aid in assessment of serostatus to infection with T. gondii and immune status of pregnant women. 
• Results are reported as negative, positive or equivocal.  Repeat testing on a sample collected at least one to two weeks after the first equivocal results is recommended.   
• Toxoplasma IgM testing should be conducted in parallel with this IgG test. 
• The interpretation and recommended follow up testing are outlined in the following table:

_{*except infants}

NCCLS. Clinical Use and Interpretation of Serologic Tests for Toxoplasma gondii; Approved Guideline. NCCLS document M36-A [ISBN 1-56238-523-2].