Thyroperoxidase Antibody

Tube Type

Test ID		LAB858
EPIC Order		Thyroid Peroxidase Antibody
CPT Code(s)		86376
Group/Individual Test		Individual
Laboratory		Core Laboratory - Chemistry
Tube Station		30
Specimen	Routine:	4 mL blood/gold SST tube; See Comments
	Micro:	1 mL blood/gold SST tube; See Comments
Stability	Spun/Separated	Room Temperature: 8 hours Refrigerated: 7 days Frozen: 6 months
Availability	Routine:	24 / 7
Turnaround Time		2 hrs
Reference Range		less than or equal to 10.4 IU/mL was established as a cut-off value to differentiate between TPO Antibody Positive and TPO Antibody Negative
Comments	Low levels of Thyroid Peroxidase Antibody can be detected in healthy individuals with normal thyroid function. This test is performed using the Siemens Atellica IM aTPOII assay (effective 8/7/2026) and results are not interchangeable with other systems. Patient samples may contain heterophilic antibodies that could react with immunoassays to give falsely elevated or depressed results. Results of this assay should always be interpreted in conjunction with patient's medical history, clinical presentation, and other findings. Performance of this assay has not been established with neonatal specimens. Please see memo Core #235 for more information

Reviewed by J. Carr on August 10, 2026

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514