Sex Hormone Binding Globulin

Mint Green Plasma Separator Tube

Tube Type

Test ID   LAB5751
EPIC Order
CPT Code(s)   84270
Group/Individual Test   Individual
Laboratory   Core Laboratory
Tube Station   30
Specimen Routine: 3 mL blood/Li Heparin plasma separator tube/Mint Green top. Also acceptable serum (Gold SST / Red Top Tube)
Stability Spun/ Separated

Room temperature: 4 hours

Refrigerated: 6 days

Frozen: 6 months

Availability Routine: 24/7
Turnaround Time  
Reference Range Normal: See below

Reference Range SHBG (nmol/L)

Female Male
Age <50 years 18-138 11-54
Age >50 years 24-110 17-72

For unknown, unspecified or transgender patients, both male and female reference ranges will be reported.


Testing is performed using Siemens Atellica SHBG Assay. Patient samples may contain heterophilic antibodies that could react in immunoassays to give falsely elevated or depressed results.  This assay is designed to minimize interference from heterophilic antibodies.

In patients receiving high doses of biotin (>5 mg/day), no sample should be taken within 8 hours of biotin administration.

Reviewed by jcayless on December 28, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514