Alert

HIV Ag/Ab Combo

Tube Type

Test ID LAB5169
EPIC Order
HIV Antigen/Antibody Combo
CPT Code(s) 87389, (with 86703, Geenius, if positive)
Group/Individual Test Individual
Laboratory Clinical Immunology
Tube Station 30
Specimen Routine:
5 mL blood/serum separator tube/gold top;
(see comments for additional information).
Micro: 3 serum separator bullets
Availability Routine: Monday-Friday
STAT: See Needlestick Protocol
Turnaround Time 24-72 hours (negative tests)
Reference Range Normal: Negative
Critical Value:
Positive (following confirmatory testing)

Internal Reference Testing Specimen Handling Instructions:

Centrifuge, Refrigerate
Comment Specimens submitted for HIV antibody testing are assayed using the Abbott Architect HIV Ag/Ab Combo test. The test provides qualitative detection of HIV-1 and HIV-2 antibody as well as HIV-1 p24 antigen simultaneously on an automated platform. It is intended as an aid in the diagnosis of HIV-1/2 infection and acute HIV-1 infection. It is not approved for use in patients less than 2 years of age. Results are reported as either nonreactive for HIV-1/2 antibody and HIV-1 p24 antigen, reactive or indeterminate based on the HIV-1/2 Combo result in conjunction with reflexed follow up testing. Samples with reactive HIV-1/2 Combo results are reflexed to the BioRad HIV-1/2 Geenius assay to differentiate HIV-1 from HIV-2 antibody. Results will state whether the patients is reactive to HIV-1 or HIV-2. Samples that are reactive by the HIV ag/ab combo and are negative or indeterminate by Geenius are reflexed to HIV-1 viral load testing to assess the patient for acute HIV-1 infection. See HIV Testing Algorithm.

Reviewed by gloria_crawford on October 25, 2017

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514

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