Vaccine information, visitor restrictions, and additional resources | Medicaid: The program is changing and you must take steps to keep your UNC Health providers

HBsAg (Hepatitis B Surface Antigen)

Tube Type

Test ID   LAB471
EPIC Order
CPT Code(s)   87340 (with 87341, neutralization, if positive)
Group/Individual Test   Individual
Laboratory   Clinical Immunology
Tube Station   30
Specimen Routine: 2 mL blood/Serum Separator Tube/Gold Top
 Availability Routine: Monday-Friday; See Comments for additional information

Stat requests require a phone call to the lab: 984-974-1815 (Mon-Sat 8am to 4pm); 984-9741-1805 (after hours).  Supervisor/Director approval  may be required.

(L&D only)

Turnaround Time   1 - 3 Days
Reference Range Normal: Negative
Comment Specimens submitted for detection of HBsAg are tested using a chemiluminescent microparticle immunoassay (CMIA).   This automated assay on the Abbott Architect system provides a qualitative determination of the presence of HBsAg.  Results are reported as non-reactive or reactive.  Reactive results are only reported when the presence of HBsAg is confirmed with the HBsAg confirmation (neutralization) assay.  Successful confirmation is indicated by the result “reactive, confirmed by neutralization”.  Results of this test should be used in conjunction with other serologic tests for HBV for the diagnosis of acute and chronic HBV infection.  A nonreactive result does not rule out infection as the HBsAg may be below the limits of detection or not react with the antibodies in this assay.

Reviewed by jcayless on December 02, 2019

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514