HBsAg (Hepatitis B Surface Antigen)

Tube Type

Test ID LAB471
CPT Code(s) 87340 (with 87341, neutralization, if positive)
Group/Individual Test Individual
Laboratory Clinical Immunology
Tube Station 30
Specimen Routine: 2 mL blood/Serum Separator Tube/Gold Top
Availability Routine: Monday-Friday; See Comments for additional information

Stat requests require a phone call to the lab: 984-974-1815 (Mon-Sat 8am to 4pm); 984-974-1805 (after hours).Supervisor/Director approval may be required.

(L&D only)

Turnaround Time 1 - 3 Days
Reference Range Normal: Negative
Comment Specimens submitted for detection of HBsAg are tested using a chemiluminescent microparticle immunoassay (CMIA). This automated assay on the Abbott Architect system provides a qualitative determination of the presence of HBsAg. Results are reported as non-reactive or reactive. Reactive results are only reported when the presence of HBsAg is confirmed with the HBsAg confirmation (neutralization) assay. Successful confirmation is indicated by the result “reactive, confirmed by neutralization”. Results of this test should be used in conjunction with other serologic tests for HBV for the diagnosis of acute and chronic HBV infection. A nonreactive result does not rule out infection as the HBsAg may be below the limits of detection or not react with the antibodies in this assay.

Reviewed by Christopher Parker on November 30, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514