Published on April 02, 2015


Tube Type

Test ID   LAB875A
CPT Code(s)   80169
Group/Individual Test   Individual
Laboratory   Performed by: Special Chemistry Laboratory
Tube Station   30
Specimen Routine: 5 mL blood/lavender top blood collection tube; see Comments
  Micro: 500 µL blood/lavender top microcollection device
Stability Room Temperature: 14 days
Off Site Collections:
Ambient/Room Temp. is acceptable. Samples may be refrigerated (2 - 8°C). Do NOT freeze.  Ship ambient or with refrigerated cold pack(s) only. Do NOT use dry ice. Do NOT use frozen cold packs.
Ambient: 14 Days
Refrigerated: 14 Days
Frozen - Not Acceptable
Availability Routine: Daily; Not available STAT
Turnaround Time   Samples for Everolimus testing must be in the Core Laboratory by 12pm(noon) for same day testing. Results available by ~5pm.
Reference Range   >3-15 ng/mL (Trough, steady state).
Critical Value Range

Everolimus: Greater than 20 ng/mL

The above ranges are published as rough guidelines only. Concentrations targeted depend upon the drug regimen used, the type of transplant, time post transplantation, and other clinical factors such as renal function, rejection status, etc.


 Methodology: Liquid Chromatography Tandem Mass Spectrometry

-Everolimus should be collected as a trough sample immediately before the next scheduled dose.

-Multiple test requests with same sample type will require additional volumes for testing.

-Pediatric microcollection devices available from Phlebotomy Services

Reviewed by Christopher Parker on March 29, 2022

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514