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Published on April 02, 2015

Everolimus

Tube Type = Lavendar Top

Tube Type

Test ID   LAB875A
EPIC ORDER
   EVEROLIMUS
CPT Code(s)   80169
Group/Individual Test   Individual
Laboratory   Performed by: Special Chemistry Laboratory
Tube Station   30
Specimen Routine: 3 mL blood/lavender EDTA tube; See Comments
Micro: 500 µL blood/lavender EDTA microtainer
Stability Room Temperature 14 days
 Refrigerator (2-8°C) 14 days
Frozen: NOT ACCEPTABLE
Off Site Collections: Ambient/Room Temperature is acceptable. Samples may be refrigerated (2 - 8°C). Do NOT freeze. Ship ambient or with refrigerated cold pack(s) only. Do NOT use dry ice. Do NOT use frozen cold packs.
Availability Routine: Daily; Not available STAT
Turnaround Time   Samples for Everolimus testing must be in the Core Laboratory by 12pm(noon) for same day testing. Results available by ~5pm.
Reference Range   >3-15 ng/mL (Trough, steady state).
Critical Value Range

Everolimus: Greater than 20 ng/mL

The above ranges are published as rough guidelines only. Concentrations targeted depend upon the drug regimen used, the type of transplant, time post transplantation, and other clinical factors such as renal function, rejection status, etc.
Comments
  • Methodology: Liquid Chromatography Tandem Mass Spectrometry
  • Everolimus should be collected as a trough sample immediately before the next scheduled dose
  • Multiple test requests with same sample type will require additional volumes for testing
  • Pediatric microtainer devices available from Phlebotomy Services

Reviewed by J.Carr on November 14, 2025

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514