Published on April 02, 2015

Cyclosporine, Trough

Tube Type

Test ID   LAB5343
CPT Code(s)   80158
Group/Individual Test   Individual
Laboratory   Performed by: Special Chemistry Lab
Tube Station   30
Specimen Routine: 5 mL blood/lavender top blood collection tube
  micro: 500 µL blood/lavender top microcollection device

Room Temperature: 14 days

Off Site Collections:
Ambient/Room Temp. is acceptable. Samples may be refrigerated (2 - 8°C). Do NOT freeze.  Ship ambient or with refrigerated cold pack(s) only.  Do NOT use dry ice. Do NOT use frozen cold packs.
Ambient: 14 Days
Refrigerated: 14 Days
Frozen - Not Acceptable
Availability Routine: Daily; Not available STAT; see Comments
 Turnaround Time  
-Samples must be received in the Core Laboratory by 12:00 PM for same day testing.
-Results available by ~5pm
Reference Range  

100-400 ng/mL (trough, steady state)

The above ranges are published as rough guidelines only. Concentrations targeted depend upon the drug regimen used, the type of transplant, time post transplantation, and other clinical factors such as renal function, rejection status, etc.

Critical Range >800 ng/mL

Method: Liquid Chromatography Tandem Mass Spectrometry

Trough samples are used for routine monitoring, and should be collected immediately before the next dose.

Multiple test requests with same sample type will require additional volumes for testing.
Pediatric microcollection devices available from Phlebotomy Services

Reviewed by Christopher Parker on November 01, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514