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Published on April 02, 2015

Cyclosporine, Trough

Tube Type = Lavender Top Blood Collection Tube

Tube Type

Test ID   LAB5343
EPIC ORDER
   CYCLOSPORINE, TROUGH
CPT Code(s)   80158
Group/Individual Test   Individual
Laboratory   Performed by: Special Chemistry Lab
Tube Station   30
Specimen Routine: 3 mL blood/lavender EDTA tube; See Comments
Micro: 500 µL blood/lavender EDTA microtainer
Stability Room Temperature 14 days
2-8°C 14 days
Frozen: NOT ACCEPTABLE
Off Site Collections: Ambient/Room Temp. is acceptable. Samples may be refrigerated (2 - 8°C). Do NOT freeze. Ship ambient or with refrigerated cold pack(s) only. Do NOT use dry ice. Do NOT use frozen cold packs.
Availability Routine: Daily; Not available STAT; see Comments
 Turnaround Time  
-Samples must be received in the Core Laboratory by 12:00 PM for same day testing.
-Results available by ~5pm
Reference Range  

100-400 ng/mL (trough, steady state)

The above ranges are published as rough guidelines only. Concentrations targeted depend upon the drug regimen used, the type of transplant, time post transplantation, and other clinical factors such as renal function, rejection status, etc.
Critical Range >800 ng/mL
Comments
  • Method: Liquid Chromatography Tandem Mass Spectrometry
  • Trough samples are used for routine monitoring and should be collected immediately before the next dose.
  • Multiple test requests with the same sample type will require additional volumes for testing.
  • Pediatric microtainer devices available from Phlebotomy Services

Reviewed by J. Carr on November 14, 2025

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514