Alert

Predictive Information for Streptococcus pneumoniae Susceptibility Tests

Penicillin susceptibility data may be used to predict susceptibility to the following antimicrobials:

For NON-MENINGEAL pneumococcal isolates, penicillin susceptible by screen or penicillin MICs of <=0.06 predict susceptibility to: ampicillin (oral or parenteral), ampicillin-sulbactam, amoxicillin, amoxicillin-clavulanic acid, cefaclor, cefdinir,cefditoren, cefepime, cefotaxime, cefpodoxime, cefprozil,  ceftaroline, ceftizoxime, cefuroxime, doripenem, ertapenem, imipenem, loracarbef and meropenem.

For additional information, please contact the Clinical Microbiology Laboratory at 984-974-1805.

Reference:

Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; 35rd Edition. CLSI Document M100. CLSI, Wayne, PA, 19087, USA, 2025

Reviewed by J. Carr on December 05, 2025

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514