C1 Esterase Inhibitor, Antigen

Tube Type

Test ID LAB850
EPIC Order
CPT Code(s) 83883
Group/Individual Test Individual
Laboratory Core Referral Testing
Tube Station 30
Specimen Routine: 3 mL blood/red top tube; see important Comments
micro: 1.5 mL blood
Availability Routine: Reference Laboratory - Mayo Clinic Laboratories
Turnaround Time 3-5 days
Reference Range Normal: See separate report

Patient should be fasting (12 hour fast preferred); serum separator tube (gold top) acceptable.

Patients being investigated for a deficiency of C1 Esterase Inhibitor can be effectively screened with serum concentration of C4. A C4 within the reference range has a 99% negative predictive value for the diagnosis of C1 esterase inhibitor deficiency (Gompels MM, Lock RJ, Morgan JE, et al. A multicentre evaluation of the diagnostic efficiency of serololgical investigations for C1 inhibitor deficiency. J Clin Pathol 2002; 55:145-147)

Reviewed by jcarr on December 03, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514