C1 Esterase Inhibitor, Antigen

Tube Type

Test ID		LAB850
EPIC Order		C1 ESTERASE INHIBITOR ANTIGEN
CPT Code(s)		83883
Group/Individual Test		Individual
Laboratory		Core Referral Testing
Tube Station		30
Specimen	Routine:	3 mL blood/red top tube; see important *Comments*
	micro:	1.5 mL blood
Availability	Routine:	Reference Laboratory - Mayo Clinic Laboratories
Turnaround Time		3-5 days
Reference Range	Normal:	See separate report
Comments		*Patient should be fasting (12 hour fast preferred); serum separator tube (gold top) acceptable.* Patients being investigated for a deficiency of C1 Esterase Inhibitor can be effectively screened with serum concentration of C4. A C4 within the reference range has a 99% negative predictive value for the diagnosis of C1 esterase inhibitor deficiency (Gompels MM, Lock RJ, Morgan JE, et al. A multicentre evaluation of the diagnostic efficiency of serololgical investigations for C1 inhibitor deficiency. J Clin Pathol 2002; 55:145-147)

Reviewed by J. Carr on December 13, 2023

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514