C1 Esterase Inhibitor, Functional

Tube Type on ice

Test ID   LAB769
CPT Code(s)   83520
Group/Individual Test   Individual
Laboratory   Core Referral Testing
Tube Station   30
Specimen Routine: 4 mL blood/red top tube on ice; See important comments 
  micro: 0.5 mL blood
Availability Routine: Reference Laboratory -  Mayo Clinic Laboratories
Turnaround Time   5-7 days
Reference Range Normal: See separate report

Deliver immediately: Sample must be processed within 30 minutes of collection.

Patient should be fasting (12 hour fast preferred)

Patients being investigated for a deficiency of C1 Esterase Inhibitor can be effectively screened with serum concentration of C4. A C4 within the reference range has a 99% negative predictive value for the diagnosis of C1 esterase inhibitor deficiency (Gompels MM, Lock RJ, Morgan JE, et al. A multicentre evaluation of the diagnostic efficiency of serololgical investigations for C1 inhibitor deficiency. J Clin Pathol 2002; 55:145-147)

Reviewed by jcarr on December 03, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514