LIAISON PLEX BCN limitations and cross-reactive species
- Detection of the Enterobacteriaceae/Morganellaceae family target alone in the absence of a genus or species indicates that the assay detected the gene target for Enterobacteriaceae/Morganellaceae, but the genus or species could not be differentiated. Additional testing is necessary for species -level identification.
- Detection of resistance gene(s) in a specimen does not confirm that the resistance marker is associated with the organism(s) detected. Sub-culturing and subsequent testing of the isolated organism are necessary to definitively link antimicrobial resistance with a specific organism.
- Reports with multiple organisms detected should be interpreted with caution. Refer to culture for definitive results.
- The LIAISON PLEX Gram-negative Blood Culture (BCN) Assay can cross-react with several organisms, typically closely related or near-neighbor species to those detected by the panel. Confirmed or predicted cross-reactive species are included in the table below.
|
Organism
|
Potential BCN Result
|
| Serratia spp. (non-marcescens) |
Serratia marcescens |
| Klebsiella aerogenes |
Enterobacter spp. |
| Shigella spp. |
Escherichia coli |
|
Some strains of Aeromonas, Aggregatibacter, Corynebacterium, Haemophilus, and Pseudomonas
|
Enterobacteriaceae/Morganellaceae
|
|
Some strains of Escherichia,
Raoultella, and Shigella
|
Citrobacter spp. |
|
Some strains of Klebsiella,
Leclercia, and Lelliottia
|
Enterobacter spp.
|
Some strains of Cedecea,
Enterobacter, Escherichia, other Klebsiella species, Kluyvera, and
Raoultella
|
Klebsiella oxytoca
|
|
Some strains of Haemophilus,
Leclercia, Morganella, Providencia
and Serratia
|
Proteus spp.
|
|
Some strains of
Enterobacter cloacae and other Stenotrophomonas species |
Stenotrophomonas maltophilia
|
Ralstonia pickettii
|
Klebsiella
oxytoca, Proteus spp, Enterobacter spp., E. coli, Citrobacter spp.
|