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Published on March 17, 2021

Dysautonomia, Autoimmune/Paraneoplastic Eval, Serum

Includes:  AChR Ganglioninc Neuronal AB S, Anti-Neuronal Nuclear Ab Type 1, CASPR2-IgG CBA S, CRMP-5-IgG S, DPPX Ab IFA S, DPPX Ab CBA, LGI1-IgG CBA S, Purkinje Cell Cytoplasmic Ab Type 2, AP3B2 IFA

Reflexed Tests:  ANNA-1 Immunoblot S, ANNA-2 Immunoblot S, CRMP-5-IgG Western Blot S, DPPX Ab CBA S, DPPX AB IFA Titer S, AP3B2 CBA, CRMP-5-IgG titer, ANNA-1 titer, AP3B2 IFA titer, PCA-2 titer

Tube Type = Red Top

x2
Tube Type

Test ID   LAB11401
EPIC ORDER
  Dysautonomia, Autoimmune/Paraneoplastic Eval, Serum
CPT Code(s)   83519, 86255x7 (84182x3, 86255x2, 86256x5, if appropriate)
Group/Individual Test   Group
Laboratory   Core Referral Testing
Tube Station   30
Specimen Routine: 10 mL blood/red plain tube/gold SST tube also acceptable; See Comments
  Micro: 7.5 mL blood
Availability Routine: Reference Laboratory - Mayo Clinic Laboratories
Turnaround Time   12-14 days
Reference Range Normal: See separate report
 Comments
  • For optimal antibody detection, specimen collection is recommended before initiation of immunosuppressant medication or intravenous immunoglobulin treatment. 
  •  This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. The specific waiting period before specimen collection will depend on the isotope administered, the dose given, and the clearance rate is the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held 1 week and assayed if sufficiently decayed or canceled or radioactivity remains. 
  • Patient should have no general anesthetic or muscle-relaxant medications in the previous 24 hours. 

Reviewed by J. Carr on December 11, 2025

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514