Anti-HCV (Hepatitis C Antibody)

Tube Type

Test ID LAB868
CPT Code(s) 86803
Group/Individual Test Individual
Laboratory Clinical Immunology
Tube Station 30
Specimen Routine: 2 mL blood/Serum Separator Tube/Gold Top X 2: (2 Tubes to accommodate possible reflex testing).
Availability Routine: 7 days
Turnaround Time 1- 3 Days
Reference Range Normal: Negative

Specimens submitted for Hepatitis C virus (HCV) antibody testing are assayed using a chemiluminescent microparticle immunoassay for the determination of IgG and IgM antibodies against recombinant Hepatitis C virus proteins on the Abbott Architect system. Results are reported as nonreactive, reactive or equivocal. This assay provides a qualitative determination of HCV antibody which, if detected, provides presumptive evidence of HCV infection. However, the presence of antibody alone cannot distinguish resolved infection from current infection.

Reactive and equivocal samples are automatically reflexed to HCV RNA viral load testing for confirmation of HCV infection status. See HCV testing guidelines for additional information.

HCV Antibody Result HCV RNA Result Interpretation/Further Action
Non-reactive Not indicated Non-reactive for HCV antibody. No further action necessary unless recent exposure is suspected.

For immunocompromised, consider HCV RNA testing


RNA detected Current HCV infection. Counsel appropriately and link to care

RNA not detected

No current HCV infection. No further action required.

If distinction between true positive and false positive HCV antibody screening test is desired, test with a different HCV antibody assay (contact referral testing laboratory (984-974-1414) for further information).

If exposure within last 6 months is suspected or there is clinical evidence of HCV disease, follow up HCV RNA testing is recommended.

Reviewed by Christopher Parker on November 30, 2021

Note: Reference ranges provided on this web site are for guidance only, and may not reflect the most recent changes. Refer to laboratory reports for current reference data.

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514