Anti-HBc IgM (Hepatitis B Core Antibody - IgM)

Tube Type

Test ID		LAB549
EPIC Order		HEPATITIS B CORE ANTIBODY, IGM
CPT Code(s)		86705
Group/Individual Test		Individual
Laboratory		Clinical Immunology
Tube Station		30
Specimen	Routine:	2 mL blood/Gold SST tube
Availability	Routine:	Monday - Friday
Turnaround Time		1 - 3 days
Reference Range		Non-reactive
Comment		Specimens submitted for detection of IgM antibody to HBV Core Antigen (IgM anti-HBc) are tested using a chemiluminescent microparticle immunoassay (CMIA). This assay provides qualitative detection of IgM antibodies against HBV core antigen in human serum using the automated Abbott Alinity-i system. It is intended for use in the diagnosis of acute/recent HBV infection. Results are reported as nonreactive, reactive or grayzone. Additional specimens collected at weekly intervals are recommended for initially grayzone specimens. Testing these specimens may help to differentiate early acute infection associated with rapidly rising IgM from late acute infection associated with declining or unchanging IgM levels.

Reviewed by J. Carr on November 03, 2025

UNC Hospitals
McLendon Clinical Laboratories
101 Manning Drive
Chapel Hill, NC 27514